NADX³ is an advanced cellular rejuvenation complex designed for professional aesthetic treatments. Optimized for microneedling (MTS) and transdermal delivery, it combines NAD⁺ activation, regenerative support, and antioxidant protection to help improve skin vitality, hydration, firmness, and overall skin quality.
Cellular Energy Activation
Skin Regeneration Support
Brightening & Antioxidant Defense
NAD⁺(Nicotinamide Adenine Dinucleotide) is an essential coenzyme present in every living cell, driving over 500 enzymatic reactions.
It is central to cellular energy production, DNA repair, and the activation of longevity-associated proteins called Sirtuins.
Critically, NAD⁺ levels decline by approximately 50% between age 20 and 50, and by up to 80% by age 80 - making its restoration one of the most clinically relevant targets in aesthetic longevity medicine
NAD⁺ decline by age 50
NAD⁺ decline by age 80
Enzymatic reactions
requiring NAD⁺
Sirtuin longevity proteins
activated by NAD+
A highly bioavailable NAD+ precursor
that supports mitochondrial function
and efficient NAD+ production.
Supports cellular energy metabolism and
plays a key role in DNA repair and skin vitality.
A direct precursor that rapidly converts
into NAD+ inside cells,
helping boost cellular activity and regeneration.
NAD⁺ , NMN, and NR are essential molecules involved in cellular energy production and regeneration. Together, they form a powerful system that supports the skin from within by restoring declining NAD⁺ levels.
INTRACELLULAR NAD+ BIOSYNTHESIS PATHWAY
The active coenzyme responsible for cellular energy and repair.
A fast-acting precursor that restores NAD+ levels within cells.
Sustained salvage-pathway precursor
MW 663 g/mol
MW 334 g/mol
MW 255 g/mol
Supports natural recovery
Plumped, supple appearance
Smoother, fuller complexion
Visibly tighter, lifted skin
Three complementary antioxidants targeting different points in the oxidative stress pathway - providing protection against premature aging, uneven tone, and environmental damage that single-ingredient formulas cannot match.
Radiance & luminosity boost
Supports collagen formation
A powerful antioxidant and essential cofactor for collagen synthesis enzymes. Neutralizes UV-induced free radicals and inhibits melanin production at the dopaquinone step — visibly brightening and evening skin complexion.
Brightens uneven skin tone
Free radical scavenging
The body's master antioxidant tripeptide. Neutralizes free radicals and peroxides, while inhibiting tyrosinase activity - shifting melanin production toward lighter phaeomela
Reduces dark spots & pigmentation
Strengthens skin barrier
A multifunctional B vitamin and NAD+ precursor. Inhibits melanosome transfer between cells — visibly reducing dark spots. Strengthens the skin barrier by promoting ceramide synthesis, and minimizes the appearance of pores.
Oxidative stress
Neutralizes superoxide
& singlet oxygen
Luminous, even skin
Scavenges hydroxyl radicals,
resets Vitamin C
Brighter, clearer tone
Blocks pigment transfer,
reinforces skin barrier
Even tone, refined pores
Skin Dehydration
Dermal Atrophy
Stretch Striae
Skin Dullness
Skin Laxity
Acne Scarring
Photo Aging
Barrier Sensitivity
Face
A series of 3 sessions is recommended
at intervals of 1‒2 weeks.
Approximately 3 ml per session,
depending on the treatment area
and protocol.
For Partnership inquiries and to explore how we can work together.
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