Genese Labs

Proluma PLA

Enhance natural collagen, improve skin texture, and
reveal your youthful radiance with Proluma

Enhance natural collagen, improve skin texture, and reveal your youthful radiance with Proluma

Proluma PLA, a cutting-edge natural collagen stimulator designed to rejuvenate skin texture gradually. Proluma PLA boasts a unique formulation with perfect spherical shapes and uniform particle size, requiring lower injection power.

This innovative product utilizes Genese Labs exclusive freeze-drying technique, significantly reducing treatment time by allowing for quicker dissolution. Crafted with biodegradable materials, Proluma PLA ensures no residue is left in the body over time, offering a safe, efficient, and groundbreaking solution for skin rejuvenation.

Benefits

Next Generation PLA Filler

Reduce treatment time due to


faster filler dissolution.

Soft injection due to uniform


particle size and long-lasting


power due to heavier molecular


weight of more than 200,000DA.

Even volume creation through


spherical PLA particles.

High safety due to the use of


biocompatible and eco-friendly


material.

Benefits

Next Generation PLA Filler

Reduce treatment time due to faster filler dissolution.
Soft injection due to uniform particle size and long-lasting power due to heavier molecular weight of more than 200,000DA.
Even volume creation through spherical PLA particles.
High safety due to the use of biocompatible and eco-friendly material.

Why PDLLA ?

A key feature of PDLLA is its role in stimulating collagen production, an essential process for tisue regeneration and healing. PDLLA is recognized for its safety, having received approval from the US FDA and classified under its GRAS (Generally Recognized as Safe) designation since 1984.

Collagen Production

Stimulated by the presence of immune cells and the degradation products of PDLLA, fibroblasts begin to produce and organize new collagen fibers.

Tissue Regeneration

Over time, as PDLLA completely degrades and is replaced by newly formed tissue, the collagen structure becomes more organized, restoring the tissue's strength and functionality.

Fibroblast Activation

Among the immune cells attracted to the site are fibroblasts, which play a crucial role in wound healing and tissue regene -ration. Fibroblasts are responsible for producing collagen, the primary structural protein in connective tissues.

Efficiency of ProlumaTMPLA

1

New Tissues and Collagen Production

Proluma effectively promotes the generation of new tissues and collagen, demonstrating a progressive cellular response to the treatment:

2

Long Lasting Effect

Proluma stands out by not only correcting wrinkles and folds but also ensuring lasting volumization across facial areas, offering a durable alternative to traditional fillers that target specific folds. Its effectiveness in enhancing natural facial volume through the stimulation of new collagen and tissue production contributes to its long-lasting results.

3

Safety: Biodegradability

PDLLA, known for its safety and non-toxic properties, undergoes degradation in the body via hydrolysis, breaking down into lactic acid and glycogen. Through metabolic processes, PDLLA is further decomposed into carbon dioxide and water, which are then safely excreted from the body.

PDLLA is recognized for its safety, having received approval from the US FDA and classified under its GRAS (Generally Recognized as Safe) designation since 1984.

How to Use

Suspension

Thirty minutes before the procedure, prepare a 9cc suspension by combining 7cc of Sterile Water For Injection (SWFI) and 2cc of lidocaine with the contents of the Proluma vial.

Remove cap and clean

Remove the flip-off cap and sanitize the penetrable vial stopper using an antiseptic.

Mix with Sterile Water For Injection(SWFI)

Connect an 18G needle to a sterile, single-use 7-mL syringe and draw 7 mL of Sterile Water For Injection (SWFI) into the syringe. Invert the vial, insert the needle through the stopper, and gradually inject the SWFI into the vial

Agitate the vial upright prior to injection

Vigorously shake the vial by hand or use a single vial swirling agitator for approximately 1 minute to dissolve the excipients. Examine the vial for any undissolved lumps and, if necessary, continue shaking until they are dissolved.

Mix with Sterile Water For Injection(SWFI)

Immediately before treatment, cleanse the rubber cap of Proluma. Introduce 2cc of Lidocaine and then fill with the diluted solution using an 18G needle. It is important not to store the solution within the syringe for an extended period.

Withdrawing the suspension

Sanitize the stopper of the vial, then use an 18G single-use, sterile syringe, either 1-or 3-mL, to withdraw the suspension.

Switching to a 25G or 26G needle

Before proceeding with the injection, replace the needle with a sterile 250 or 26G needle.

How to Use

Suspension

Thirty minutes before the procedure, prepare a 9cc suspension by combining 7cc of Sterile Water For Injection (SWFI) and 2cc of lidocaine with the contents of the Proluma vial.

Remove cap and clean Remove the flip-off cap and sanitize the penetrable vial stopper using an antiseptic.
Mix with Sterile Water For Injection(SWFI) Connect an 18G needle to a sterile, single-use 7-mL syringe and draw 7 mL of Sterile Water For Injection (SWFI) into the syringe. Invert the vial, insert the needle through the stopper, and gradually inject the SWFI into the vial
Agitate the vial upright prior to injection Vigorously shake the vial by hand or use a single vial swirling agitator for approximately 1 minute to dissolve the excipients. Examine the vial for any undissolved lumps and, if necessary, continue shaking until they are dissolved.
Mix with Sterile Water For Injection(SWFI) Immediately before treatment, cleanse the rubber cap of Proluma. Introduce 2cc of Lidocaine and then fill with the diluted solution using an 18G needle. It is important not to store the solution within the syringe for an extended period.
Withdrawing the suspension Sanitize the stopper of the vial, then use an 18G single-use, sterile syringe, either 1-or 3-mL, to withdraw the suspension.
Switching to a 25G or 26G needle Before proceeding with the injection, replace the needle with a sterile 250 or 26G needle.

Application Area

Dry, thin skin with fine wrinkles

Nasolabial folds

Inject into the deep dermis layer, where this method actively stimulates collagen production more effectively than conventional fillers.

Application Area

Inject into the deep dermis layer, where this method actively stimulates collagen production more effectively than conventional fillers.

Before and After

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